Genetic DNA Test Estrogenomic Profile
The metabolism of oestrogen is an important process that involves phase 1 and 2 enzymes of the liver which are responsible for the formation of pro- and anti-carcinogenic metabolites as well as their removal. Raised levels of these metabolites could be indicated in an increased risk of breast cancer and osteoporosis.
Variations and mutations of genes that are responsible for the interaction of oestrogen with clot formation and fibrinolysis process can over-activate blood clotting processes. Therefore increasing the risk of sudden cardiac events such as thrombosis, heart attacks, and strokes.
These genes affect how the body processes cholesterol, responds to inflammation, and metabolizes B vitamins. The presence of these SNPs can increase risk of cardiovascular disease, hyperlipidemia, and blood vessel damage.
This profile covers the genetic susceptibility to the following diseases and conditions:
- Breast cancer
- Heart Disease
- What is being measured
- Age range this test is suitable for
- Specimen Requirement
- Before taking this test
- How long until I get my results
- Sample report
- APOE (Apoliprotein E)
- COMT (Catechol-O-Methyl Transferase)
- CYP1A1 (Cytochrome P-450)
- CYP1B1 (Cytochrome P-450)
- Factor 2 (Prothrombin)
- Factor 5 (Leiden)
- GP3a (Glycoprotein 3)
- GST (M1 and P1) (Glutahione s-Transferase)
- IL-6 (Interleukin-6)
- MTHFR (Methylenetetrahydrofolate Reductase)
- PAI-1 (Plasminogen Activator Inhibitor-1)
- TNF-a (Tumor Necrosis Factor-alpha)
- VDR (Vitamin D3 receptor)
Adults over 18
Buccal – swab
The buccal swab is designed to collect some loose cells in your mouth. Brush your teeth the night before the test. Do not eat any food after you have brushed your teeth. Upon awakening for the day of collection, do not brush your teeth, eat or drink anything prior to the sample collection.
See instructions inside test kit for details
All sample reports are for representational and educational purposes only. Biomarkers, references ranges, results, and all other data may differ from actual reports. All data included in no way represents an actual patient. Any comparisons of results to actual patients, is completely incidental.